IP6 (inositol hexaphosphate) is a naturally occurring compound found in rice bran, legumes, and other fiber-rich plants. It is known for its ability to bind excess iron, inhibit cancer cell growth, and activate natural killer (NK) cells—making it a key component of metabolic cancer therapy.

In Protocol 2, IP6 is used during the Antioxidant Wave Phase to:

  • Chelate iron, one of cancer’s most essential growth fuels
  • Inhibit angiogenesis (the formation of blood vessels that feed tumors)
  • Support NK cell activation and immune response
  • Protect DNA during the recovery window following radiation and oxidative stress

🔍 IP6 – Protocol 2 Summary

✅ Best Timing:

  • 12:30 PM during the Antioxidant Wave Phase
  • Can be combined with other antioxidants like ALA, EGCG, Resveratrol, and Curcumin
  • Avoid taking during the oxidative kill window (morning), as it may interfere with reactive oxygen therapies

💊 Recommended Dose:

  • 1000 mg once daily (standardized inositol-bound extract)
  • Take on an empty stomach or with a light, mineral-free meal (no iron, zinc, or calcium around this time)

⏳ Active Duration in Body:

  • Chelation effects begin in 1–2 hours
  • Lasts 6–8 hours for immune and iron-binding activity
  • Daily use accumulates benefit over time

🔁 Redundancy With:

  • Lactoferrin: also binds iron but via a different mechanism; they complement each other well
  • Flavonoids: IP6 is unique and does not overlap with EGCG, Curcumin, or Resveratrol mechanisms

📉 Pathways Inhibited or Affected:

  • Iron chelation: deprives tumors of iron for DNA synthesis and metabolism
  • PI3K/Akt pathway inhibition: slows down uncontrolled cell growth
  • Angiogenesis suppression: reduces new blood vessel formation
  • NK cell stimulation: enhances immune ability to detect and destroy cancer
  • Oxidative stress modulation: reduces DNA damage post-treatment

🔒 Final Summary

IP6 is a unique, iron-targeting, immune-activating compound that fits perfectly into the midday recovery strategy of Protocol 2. At 1000 mg daily, it supports remission by starving tumors of iron, reducing inflammation, and supercharging the immune system.

When used with other antioxidants and senolytics, IP6 helps rebuild and defend your body without feeding the cancer you’re trying to kill.

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