Genomic Instability in Cancer: How DNA Damage Drives Tumor Evolution

Genomic instability is one of the defining characteristics of cancer. It refers to an increased rate of DNA mutations, chromosomal rearrangements, and structural abnormalities within a cell’s genome. In healthy cells, DNA is tightly regulated and repaired when damaged. In cancer, these repair systems break down, allowing mutations to accumulate rapidly. This creates a constantly … Continue reading Genomic Instability in Cancer: How DNA Damage Drives Tumor Evolution