Resveratrol is a powerful natural polyphenol found in red grapes, red wine, and Japanese knotweed. Known for its anti-aging, anti-inflammatory, and anti-cancer properties, it has become a key tool in advanced cancer strategies due to its ability to:
- Activate SIRT1 (a longevity and DNA-repair enzyme)
- Suppress inflammatory cancer pathways
- Boost NAD+, supporting cellular energy and immune defense
- Repair oxidative damage from treatments like radiation and ROS therapy
In Protocol 2, Resveratrol plays a vital role in the Antioxidant Wave Phase—where the focus shifts from attack to recovery, mitochondrial renewal, and immune restoration.
🧬 Resveratrol – Protocol 2 Summary
✅ Best Timing:
- 12:30 PM during the Antioxidant Wave Phase
- Do not take during oxidative therapies or within 6–8 hours of:
- B17 (Amygdalin/Apricot Seeds)
- Radiation
- Artemisinin
- Methylene Blue
Pairs best with:
- Fisetin
- Quercetin
- Diosmetin
- EGCG
💊 Recommended Dose:
- 1500 mg once daily
- Use trans-resveratrol extract (superior bioavailability)
- Take with food or healthy fat for better absorption
- Optional: split into 750 mg at 12:30 PM and 750 mg with OMAD, though one full dose is ideal
⏳ How Long It Lasts:
- Effects begin within 1–2 hours
- Benefits (antioxidant, gene repair, mitochondrial support) last 6–8 hours
- Does not accumulate, so daily intake is required
🔁 Redundancy With:
- Overlaps with Pterostilbene (same SIRT1/NAD+ activation)
- Choose one, or stack for extra effect
- Shares antioxidant roles with Curcumin and EGCG
- Resveratrol stands out with unique gene-repair and anti-aging functions
📉 Pathways Inhibited or Enhanced
| Pathway | Effect |
|---|---|
| SIRT1 Activation | Supports DNA repair, anti-aging, cellular stability |
| CD38 Suppression | Conserves NAD⁺, boosting immune and mitochondrial function |
| NF-κB Inhibition | Lowers inflammation and cytokine-driven cancer signaling |
| PI3K/Akt/mTOR | Suppresses cancer cell survival and growth |
| VEGF/Angiogenesis | Reduces tumor blood vessel formation |
| Autophagy & Mitochondrial Renewal | Enhances cellular recovery post-treatment |
🧠 Final Summary: Why Resveratrol Matters in Protocol 2
Resveratrol is not just an antioxidant—it’s a genetic repair engineer and immune booster. When used at 12:30 PM during the Antioxidant Wave Phase, it helps the body:
- Clean up oxidative damage
- Restore NAD⁺ and immune function
- Shut down key cancer survival signals
- Rebuild the terrain that cancer tries to hijack
In Protocol 2, Resveratrol works best alongside Fisetin, EGCG, and Diosmetin to repair the battlefield after oxidative warfare—helping your body recover stronger and remain inhospitable to cancer recurrence.
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